Mayo Clinic uses stem cell therapy to treat arthritis in knee

Mar 24, 2019

We’re very excited to announce that researchers at the Mayo Clinic campus in Florida have made yet another stem cell breakthrough in healing chronic pain.

They have reportedly conducted the world’s first prospective, blinded and placebo-controlled clinical study to test the benefit of using bone marrow stem cells to reduce arthritic pain and disability in knees.

The Mayo Clinic believes this is the first time that stem cell and regenerative cell therapy have undergone such rigorous testing when it comes to finding relief in an ailing joint.

The researchers say such testing is needed because there are at least 600 stem cell clinics in the U.S. offering one form of stem cell therapy or another to an estimated 100,000-plus patients, who pay thousands of dollars, out of pocket, for the treatment, which has not undergone demanding clinical study.

The findings in The American Journal of Sports Medicine represent another first…

The patients in this study not only exhibited significant improvement in the knee that received stem cells, but also in their other knee, which also had painful arthritis but received only a saline control injection.

Each of the 25 patients enrolled in the study had two bad knees, but did not know which knee received the stem cells.

Although research is surfacing every day that confirms stem cells as being an effective treatment to alleviate chronic pain symptoms, researchers are still cautious about solidifying regenerative cell therapy as a recommended option for arthritic joints and bones.

“Our findings can be interrupted in ways that we now need to test — one of which is that bone marrow stem cell injection in one ailing knee can relieve pain in both affected knees in a systemic or whole-body fashion,” says the study’s lead author, Shane Shapiro, M.D., a Mayo Clinic orthopedic physician.

This is a tremendous step in the right direction and experts are quite optimistic with these initial results.

As always, we hope this serves you well!

To your health,

The Healing Miracle Team

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66 Comments

  1. debby

    Look forward to stem cell treatment for arthritic back causing sciatic nerve pain from back to ankle

    Reply
    • Aileen Devlin

      really enjoyed your recent doc series. Wondered why there was no mention of hips in the series. Is stem cell treatment currently being used to treat arthritic hips ? And if so where ?

      Reply
  2. Sean

    I have osteonecrosis of both knees. Can this treatment be available to me as well??

    Reply
    • THM Team

      While we are unable to make specific recommendations about your personal health, the experts featured in The Healing Miracle have created a Stem Hotline to provide more personalized answers. It can be found here: http://www.StemHotline.com or you can call Toll Free 1-888-414-7836 to answer the question, “Are Stem Cells Right For You?” They can connect you with a stem cell specialist in your area to help you find the solution that works best for you.

      Reply
  3. sheila

    I live in the UK, and never had anything abut stem cell treatments
    over here.
    Wonder how I could get this treatment for my knee/back pain –
    does it come in a bottle or tablet form?

    Reply
    • THM Team

      “While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition”

      Reply
  4. Sabah Kandan

    ّGood news
    I am psychiatrist but is interested in stem cell therapy. and desire to have update info.

    Reply
  5. Rosemary

    Wonderful news. I wish you had more information for those who follow you who live in Europe!

    Reply
    • THM Team

      EuroStemCell (www.eurostemcell.org) is a network of scientists and academics, providing independent, expert-reviewed information and educational resources on stem cells. They may be able to assist you in locating a clinic in our area. We encourage you to consult with your own health care provider as well, to ensure your care is in the best possible hands.

      Reply
  6. Suzanne

    Sounds really good, unfortunately I am unable to have my stem cell harvested due to medical problems and being on permanent warfarin therapy.

    Reply
  7. Jill Hogan

    I have been following this for many years so am so excited about this. Where can I access stem cell treatment in South Africa. Many thanks

    Reply
    • THM Team

      If you are outside the US, StemHotline.com also has international connections and may be able to refer you to a specialist in your area. A simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  8. Heather Limpus

    I have psoriatic arthritis. Is the clinic researching treatment for this?
    Heather

    Reply
    • THM Team

      The experts featured in The Healing Miracle have created a Stem Hotline to provide more personalized answers. It can be found here: http://www.StemHotline.com or you can call Toll Free 1-888-414-7836 to answer the question, “Are Stem Cells Right For You?” They can connect you with a stem cell specialist in your area to help you find the solution that works best for you.

      Reply
  9. Dan Van

    Hope to see if clinical studies using stem cell therapy for other autoimmune diseases will be done.

    Reply
  10. Gonzalo de Ojeda Eiseley

    Dear Sirs,

    At what else do you treat with stem cells?
    What about:
    – tinnitus
    – macular degeneration
    – rejuvenating

    Reply
    • Barbara schriver

      Will stem cells be afordable
      Soon? So many folks I know need
      Them, now. Who can they go to for stem cell help?

      Reply
  11. Jack

    Are there any studies going on in Washington DC area? I am very much interested because I had stem cell in my right knee to no success approx 8 months ago

    Reply
    • THM Team

      There is no central database for the stem cell clinics and what trials they are conducting. With a simple Google search “stem cell trials” + your region, you might find anything relevant to your area. Alternatively, you would need to check with facilities in your area.

      Reply
  12. Lani

    Happy to hear this. I need a knee replacement but am waiting for stem cells.

    Reply
  13. Patricia

    Have you heard of any treatments with Stem Cells for a spine hemangioma ?

    Reply
    • THM Team

      “While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition”

      Reply
  14. Marion

    Has any testing done on fingers and hand pain?

    Reply
    • THM Team

      Yes, there is a great deal of study in the application of stem cell treatment for pain (in all areas of the body). However, the treatment will be dependent upon the cause of the pain – injury, nerve damage, arthritis, etc.

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “stem cell + _________”)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to the particular condition causing the pain

      Reply
  15. Patrick J. McHugh

    Are they doing this at the Rochester clinic? I live in South Dakota

    Reply
    • THM Team

      The experts featured in The Healing Miracle have created http://www.StemHotline.com (or call Toll Free 1-888-414-7836) to answer the question, “Are Stem Cells Right For You?” and they can direct you to stem cell specialists in your area. A simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you.

      Reply
  16. Brenda Stuckey

    I had both knees treated with stem cells about 6 months ago. I just had an X-ray. I did not see a major change, but I do know the major pain has changed. I can stand and walk without constant pain. I am hoping this will slowly improve.

    Reply
  17. Deborah Meester

    Does this mean that in the near future insurance companies could be paying for this??

    Reply
    • THM Team

      “Stem cell research and treatments are still considered experimental in many ways. And pharmaceutical companies have been doing their best to slow (if not block) developments in this area of medical science. As a result, insurance companies do not cover the costs. It is up to all of us to encourage our insurance companies to cover it, support the research and help bring this into mainstream practice. Ask your insurance company why they don’t cover it. Tell them you want it. Explain why you need it.

      Assess the cost associated with stem cell treatment vs the costs associated with non-treatment or options available through conventional medicine.

      Conventional medicine:
      · $$$ medication (with a long list of side effects)
      · $$$ time off work
      · $$$ surgery and hospital care
      · $$$ recovery time or physio therapy
      · $$$ risk of infection, requiring more care & more medication
      · What is the prognosis for success?
      · What additional risks do you face by opting for conventional treatment?

      Most insurance companies cover a lot of these costs. While the treatment cost for stem cell treatment may have a significant price tag, the long-term, overall costs are lower.”

      Reply
  18. Sandy Johnston

    I believe stem cell therapy is wonderful but how is it available for people who can’t afford it?

    Reply
    • THM Team

      While affordability is subjective to the individual, the experts featured in The Healing Miracle have created http://www.StemHotline.com (or call Toll Free 1-888-414-7836) to answer the question, “Are Stem Cells Right For You?”. They will have more information on the costs associated with the various treatment options. As with many innovations, as it becomes mainstream practice, costs will likely reduce. Costs will vary with each treatment center and the specific treatment required.

      Reply
  19. Carol Bolin, NAP, ND

    I’m excited about this therapy; however, it needs to be accessible to more people. I believe this is currently offered by only a few doctors, correct?

    Reply
    • THM Team

      The experts featured in The Healing Miracle have created http://www.StemHotline.com (or call Toll Free 1-888-414-7836) to answer the question, “Are Stem Cells Right For You?” and they can direct you to stem cell specialists in your area. If you are outside the US, StemHotline.com also has international connections and may be able to refer you to a specialist in your area. A simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  20. Barbara Porro

    Do you have any proven science that shows stem cell benefits for fibromyalgia? My son’s condition Is systemic and chronic some days can not walk or stand very long, needs walker to get around the house.
    Thank you

    Reply
    • THM Team

      “While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition”

      Reply
  21. Debbie Coning

    Great article! Thanks so much for sharing! I think this will move the acceptance of the clinical use of stem cells forward miles!!

    Reply
  22. Marie

    I have arthritis in my right knee. It is now bone on bone. I am waiting to be able to access stem cell treatment that is affordable.

    Reply
  23. Margaret

    Do you use stem cell therapy for natural facelifts in your European clinics

    Reply
    • THM Team

      EuroStemCell (www.eurostemcell.org) is a network of scientists and academics, providing independent, expert-reviewed information and educational resources on stem cells. They may be able to assist you in locating a clinic in our area and answering your question.

      Reply
  24. Sondra Burwick

    I had stem cell injected in both knees at the Arrowhead clinic in Chandler AZ.. they were approved by the American Arthritis Association. years later, my knees are great!, I can climb stairs, and up to 3 miles on the elliptical machine.
    I’ve developed Bronchiectasis and ask if there have been any studies on using stem cell for lung conditions.

    Reply
  25. Butch

    Well its about time. Stem cells are being used around the world for decades and the “Mayo Clinic” is just getting on board?
    Its about bloody time. What needs to happen is to convience insurance companies the millions that could be saved.

    Reply
  26. Lois Brauer

    Have stem cells been used for degenerative spinal disks or spinal stenosis?

    Reply
    • THM Team

      While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition

      Reply
  27. Dance Bibanovska

    do you treat epilepsy with stem cell?

    Reply
    • THM Team

      While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition

      Reply
  28. Carol Wright

    Is stem cell treatment effective for Parkinson’s disease?

    Reply
    • THM Team

      While there is a great deal of ongoing research into the benefits of stem cell therapy for various conditions, injuries and diseases, The Healing Miracle has limited information readily available on that particular topic. We recommend:

      · searching the internet using a simple Google search to find recent articles, studies and research (ie “”stem cell + _________””)

      · join the Facebook group Stem Cells 101 and ask that community to share their experience about this condition https://www.facebook.com/groups/stemcells101/

      · visit the blog site http://www.thehealingmiracle.com to review the articles there http://www.thehealingmiracle.com/

      · contact http://www.StemHotline.com to be connected with a stem cell specialist who may have more information relating to this particular condition

      Reply
  29. Brigitte

    Are Mesenchymal fat cells (combined with PRP) as effective as bone marrow stem cells for knee treatment? I’ve read many testimonials about the high success rate of this procedure

    Reply
    • THM Team

      While we are not able to assess or offer advice on your personal health, yes, mesenchymal + PRP are often used for knee and other joint treatments with great success. Every specialist and each clinic will have their own recommendations, especially after consulting with a patient and reviewing their condition. It is always best to speak to the specialists and consult with your own trusted, health care provider before deciding what treatment is best for you.

      Reply
  30. Randy

    Thank you for providing a link to this YouTube video. However, your reference for its release is incorrect. This video was released over two years ago to be exact on Dec 6, 2016.

    Reply
    • THM Team

      Thank you for this catch, we will inform our production team.

      Reply
  31. Dan Van

    Please advise if Mayo Clinic has any plans to treat NMO with stem cells.

    Thank you.

    Dan.

    Reply
    • THM Team

      You would need to contact the Mayo Clinic for additional information.

      Reply
  32. Gillian Harper

    Where did you get the stem cells from? Was it Whartons jelly? I’m curious about the statement that you think you may be able to inject into one knee and get results in the other one day? So do you think this is just a placebo effect or are the stem cells moving beyond the the initial knee. The cost seems to stop most people from receiving stem cells at this time, do you think that will come down as studies continue or go up?

    Reply
    • THM Team

      Most of the stem cell therapy discussed in The Healing Miracle features stem cells harvested from the individual patient – in many cases from their own adipose tissue (also known as fat). There is also discussion around bone marrow stem cells and umbilical cord stem cells.

      Reply
  33. Sharon Richards

    The cost may be cheaper than surgery but I doubt that insurance companies cover it, so hence it is actually quite a bit more expensive for the patient if he has to pay out-of-pocket for it. When will insurance companies get on board with this? Also what about using stem cells from adipose tissue? That is a less painful procedure and I understand that it contains more stem cells than bone marrow does. Comments please?

    Reply
    • THM Team

      “Stem cell research and treatments are still considered experimental in many ways. And pharmaceutical companies have been doing their best to slow (if not block) developments in this area of medical science. As a result, insurance companies do not cover the costs. It is up to all of us to encourage our insurance companies to cover it, support the research and help bring this into mainstream practice. Ask your insurance company why they don’t cover it. Tell them you want it. Explain why you need it.

      Assess the cost associated with stem cell treatment vs the costs associated with non-treatment or options available through conventional medicine.

      Conventional medicine:
      · $$$ medication (with a long list of side effects)
      · $$$ time off work
      · $$$ surgery and hospital care
      · $$$ recovery time or physio therapy
      · $$$ risk of infection, requiring more care & more medication
      · What is the prognosis for success?
      · What additional risks do you face by opting for conventional treatment?

      Most insurance companies cover a lot of these costs. While the treatment cost for stem cell treatment may have a significant price tag, the long-term, overall costs are lower.”

      Reply
  34. Richad

    re: said article, showing similar improvement as the placebo knee.
    -study designed to test safety. Preliminary study.
    -might one more accurately interpret this as being no better than placebo? ie. similar benefits in both…
    -study published?

    Reply
  35. Rhonda

    Where can I find a list of doctors that do stem cell in California?

    Reply
    • THM Team

      The experts featured in The Healing Miracle have created http://www.StemHotline.com (or call Toll Free 1-888-414-7836) to answer the question, “Are Stem Cells Right For You?” and they can direct you to stem cell specialists in your area. A simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you.

      Reply
  36. Gail

    Ok this is great news….waiting for approval that bone and cartilage can be regrown!
    He did not say much about the patients…just curious if the process was temporary such as a cordizone injection.
    I want to be a future patient.

    Reply
  37. Theresa

    I am curious about Stem Cell Therapy with regards to gut health – IBS, IBD, allergies, food intolerances – imagining an infusion would reverse ill effects. Please advise, thanks!

    Reply
    • THM Team

      While we are unable to make specific recommendations about your personal health, the experts featured in The Healing Miracle have created a Stem Hotline to provide more personalized answers. It can be found here: http://www.StemHotline.com or you can call Toll Free 1-888-414-7836 to answer the question, “Are Stem Cells Right For You?” They can connect you with a stem cell specialist in your area to help you find the solution that works best for you.

      Reply
  38. Harlan Sager

    Where can I get information about stem cell studies that will pay for the treatments. I am looking at knee and hip treatments NOT replacement.

    Reply
    • THM Team

      There is no central database for the stem cell clinics around the world and what trials they are conducting. With a simple Google search “stem cell trials” + your region, you might find anything relevant to your area. Alternatively, you would need to check with facilities in your area.

      Reply
  39. Cameron Day

    No sure if it’s been mentioned – but it sounds to me that Stem cell therapy is the same as normal saline or the control/placebo. I would suggest that injecting almost anything non harmful into the knee is useful as has been tested in the past with prolotherapy (usually dextrose to attract healing factors from the blood) but taking it the step up is using PRP -platelet rich plasma which includes the healing factors from the blood.
    Interested in thoughts about this.
    Ideally though we’ll get better ways of balancing peoples bodies (especially hips and feet) and that will reduce arthritis in the first place.

    Reply

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