Researchers Discover Possible New Therapy for Hearing Loss

Jun 25, 2019

Scientists are making significant progress in the development of a new, potential method for restoring problems with hearing loss. According to the European Journal of Neuroscience, researchers have succeeded in regrowing the cells of the sensory hair located in the cochlea. The cochlea is a part of the inner ear and its function is converting sound vibrations into electrical signals. The hair cell loss can be due to advanced age as well as living in an area where there is persistent noise leading to loss of hearing.

The aging population has long accepted hearing impairment as a part of life, with approximately thirty million Americans suffering from some degree of sound loss. However, research has shown that animals such as frogs, fish, and birds can regenerate lost hair cells.

According to Jingyuan Zhang, Ph.D., a professor with the University of Rochester Department of Biology, human beings are the only vertebrates who cannot regenerate cochlea.

The research of Patricia White, Ph.D., associate professor to the Rochester Medical Center University, discovered epidermal growth factor (EGF) receptors that play the role of activating support cells to the auditory organs of birds. These receptors foster and proliferate the generation of new hair cells when triggered. White speculated that this signaling pathway has the potential to be manipulated, to produce a similar result in mammals.

White says that the cochlea of mice express EGF receptors throughout its life, but not the process of regeneration of the related hair. She speculates that during evolution, the regulators of EGF receptor family signaling might have changed the outcome hence blocking regeneration of cells. Her research is aimed at promoting hair cell regeneration and their nerve integration, which are both significant for regaining hearing.

Research conducted by scholars from the University of Rochester Medical Center and Massachusetts Ear and Eye Infirmary (of Harvard Medical School), carried out a test on the theory that the EGF family of receptors could play a role towards cochlear regeneration for mammals. The focus was particularly directed to ERBB2 receptors found on the cochlear supporting cells. Some of the experimental methods used by scholars to activate EGF receptors included using a virus to target receptors, genetically modifying mice to overexpress an activated ERBB2, and the use of two drugs previously developed for stem activity to the pancreas and eyes.

The results of these research experiments revealed that activating the ERBB2 receptor pathways triggered a series of cascading events that lead to the multiplication of cochlear supporting cells, in turn activating other neighboring stem cell division to become new hair. In addition to impacting hair regeneration, this process also promotes integration with nerve cells.

To your health,

The Healing Miracle Team

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31 Comments

  1. alan

    exciting – how to get treatment ?

    Reply
    • THM Team

      A network of stem cell specialists are available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you. If you are outside the US, they also have international connections and may be able to refer you to a specialist in your area. Additionally, a simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  2. Geno Bouwens

    OK! Is there a doctor in my area on this cutting edge?

    Sparta Michigan

    Reply
    • THM Team

      A network of stem cell specialists is available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you. If you are outside the US, they also have international connections and may be able to refer you to a specialist in your area. Additionally, a simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  3. Betty

    Where can someone look further into possibly having this done?

    Reply
    • THM Team

      A network of stem cell specialists are available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you. If you are outside the US, they also have international connections and may be able to refer you to a specialist in your area. Additionally, a simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  4. George Jacobs

    Thanks for this article! I’m 76, and a very social being. This is at the very top of my wish list!

    Reply
  5. Jacek Opienski

    Fascina and encouraging. Is this procedure available in The UK/Europe?

    Reply
    • THM Team

      EuroStemCell (www.eurostemcell.org) is a network of scientists and academics, providing independent, expert-reviewed information and educational resources on stem cells. They may be able to assist you in locating a clinic in our area. We encourage you to consult with your own health care provider as well, to ensure your care is in the best possible hands.

      Reply
  6. R

    The sooner the better.

    Reply
  7. Adrian

    I might have enjoyed it… if I’d been able to understand it!

    Reply
    • THM Team

      We are sorry to hear that you had this issue we will communicate this to our production team for further pieces.

      Reply
  8. Hazel Balcaen

    I am interested information about the treatment for cataracts because I am in the early stages of them.

    Reply
    • THM Team

      A network of stem cell specialists is available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you.

      Reply
  9. Robert Sexauer

    Do you have a list of clinics doing this therapy? I am in Missouri.

    Reply
    • THM Team

      A network of stem cell specialists are available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you. If you are outside the US, they also have international connections and may be able to refer you to a specialist in your area. Additionally, a simple Google search (“stem cell clinic” + your region) will pull up a list of treatment centers near you. Always consult your own health care provider to ensure your care is in the best possible hands.

      Reply
  10. Mary

    Yes, I enjoyed this article, it is another miracle that I am sure will happen with Stem Cells.

    Thanks!

    Reply
  11. Geraldine Mc Mahon

    The research in stem cells is absolutely amazing in its many applications. Hopefully it will be available to the population very soon.

    Reply
  12. Jane Chickos

    Fabulous!!!

    Reply
  13. Maureen

    I’ve known about this research at Harvard and an excited to know it’s progressing!

    Reply
  14. Robin Shankman

    What can stem cells do for vertigo. This is the second time I have had it and it has lasted almost two months. And how affordable are stem cell treatments?

    Reply
    • THM Team

      A network of stem cell specialists is available to provide more personalized answers – http://www.StemCellHotline.net/today. They can connect you with a stem cell specialist in your area to answer the question, “Are Stem Cells Right For You?” and to help you find the solution that works best for you.

      While affordability is subjective to the individual, a network of stem cell specialists is available to answer the question, “Are Stem Cells Right For You?” at http://www.StemCellHotline.net/today. They will have more information on the costs associated with the various treatment options. As with many innovations, as it becomes a mainstream practice, costs will likely reduce. Costs will vary with each treatment center and the specific treatment required.

      Reply
  15. Dora

    Yes I was very interested in this article because I am very hard of hearing. I have lost the lower registers completely and can not hear or understand most women.

    Reply
  16. Sherry

    Great article. My husband and I both suffer from hearing loss. I sustained vestiblar nerve damage from an ear infection and it was exacerbated by my taking Cepro antibiotic. I had profound hearing loss in one ear, then in the other. Fortunately my ENT Dr. Brant Conger acted quickly and injected steroids into the ear through the ear drum and I regained most of my hearing, but I’s still challenged in crowds and I really would like to pursue stem cells for this problem. Thank you again for opening my mind to this possibility.

    Reply
  17. Alice

    Tell me how do average people afford this care?

    Reply
    • THM Team

      While affordability is subjective to the individual, a network of stem cell specialists is available to answer the question, “Are Stem Cells Right For You?” at http://www.StemCellHotline.net/today. They will have more information on the costs associated with the various treatment options. As with many innovations, as it becomes mainstream practice, costs will likely reduce. Costs will vary with each treatment center and the specific treatment required.

      Reply
  18. Ismail Vally

    Yes. Very interesting and impressive. Hope can be successful on humans v soon

    Reply
    • Donald E. Ghidoni

      Yes

      Reply
  19. Nits

    I am experiencing thinning hair and minimal hair growth ie: underarms, legs etc. your research may help me with my hearing loss.

    Reply
  20. LEOPOLDINA

    HI . THANKS SO MUCH FOR THE BEAUTIFUL AND VERY educational READING . Keep UP THE GOOD WORK . WARM REGARDS LEOPOLDINA .

    Reply
    • THM Team

      Glad you enjoyed. Thank you for your support and encouraging words.

      Reply

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